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Path of Exile 2: The Slithering Dead Quest Guide

Author : Natalie Feb 20,2025

Path of Exile 2: The Slithering Dead Quest - A Comprehensive Guide

This guide covers the "Slithering Dead" side quest in Path of Exile 2, detailing its walkthrough and offering advice on choosing the optimal rewards. This quest, initiated by Servi in the Ziggurat Encampment, involves uncovering the secrets of a rival tribe and the fate of her son, Apus.

The Slithering Dead Quest Walkthrough

  1. Locate the Venom Crypts: Begin in the Jungle Ruins map (Act 3 and Act 3 Cruel). The Venom Crypts entrance is adjacent to the Waypoint, easily missed as it's not crucial to the main storyline. You can revisit this area even after progressing to the endgame.

  1. Explore the Venom Crypts: Thoroughly explore the Venom Crypts until you find a corpse within the Den of the Serpent Priestess. The corpse's location is randomized within the map.

  2. Retrieve the Venom: Interact with the corpse to obtain the Corpse-Snake Venom.

  3. Return to Servi: Teleport back to the Ziggurat Encampment and deliver the venom to Servi to complete the quest.

Choosing the Right Venom Draught Reward

The Slithering Dead is a repeatable quest (Act 3 and Act 3 Cruel), offering different rewards each time. The choice is permanent and irreversible.

Act 3 Rewards:

  • Venom Draught of Stone: 25% increased Stun Threshold.
  • Venom Draught of the Veil: 30% increased Elemental Ailment Threshold.
  • Venom Draught of Clarity: 25% increased Mana Regeneration Rate.

Recommendation: Venom Draught of Clarity is generally the best option, especially beneficial for melee builds often facing mana issues. Venom Draught of the Veil is a strong alternative for builds less reliant on mana. Venom Draught of Stone is the least desirable unless specifically needed to mitigate stun effects.

Act 3 Cruel (Act 6) Rewards:

  • Venom Draught of the Lost: +10% to Chaos Resistance.
  • Venom Draught of the Sky: +5 to All Attributes.
  • Venom Draught of the Marshes: 15% Reduced Slowing Potency of Debuffs.

Recommendation: Venom Draught of the Lost (+10% Chaos Resistance) is overwhelmingly the superior choice due to the rarity of Chaos Resistance on gear. Only builds utilizing Chaos Inoculation and Eternal Youth might prefer Venom Draught of the Sky for the attribute boost.

By carefully considering these choices, you can maximize the benefits from this rewarding side quest in Path of Exile 2.

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